Healthcare organizations around the world have discovered the benefits of "big data" thanks to the enormous amounts of data available from electronic health records (EHRs). Up to now, though, the data have been largely unstructured, especially in Anatomic Pathology. This has meant that it is not always easy to mine the data for effective analysis, but that is changing. Many organizations are moving towards synoptic reporting and structured data capture. The difference between the two is subtle, but important. Synoptic reports are formatted for easy consumption by the human eye while structured data are formatted to be sorted, stored, and analyzed by computers.